The Chowdhary & Cai lab (http://vetmed.tamu.edu/labs/cytogenics-genomics & http://www.genomezoo.net) is seeking a joint appointment post-doc that will apply the latest bioinformatics tools towards understanding equine diseases (including laminitis, recurrent airway obstruction, and stallion subfertility) and phenotypes. The Chowdhary lab is focusing on characterizing genetic factors involved in major equine diseases, sexual development, and reproductive disorders. The approaches applied include genetic association analysis using the equine SNP chip, microsatellites, copy number variation tiling array, re-sequencing of candidate genes, gene expression microarrays, next-generation sequencing, protein expression analysis, RT-PCR, RH mapping, karyotyping, and FISH. In addition, the lab is also working on describing the PAR and the MSY of the equine Y chromosome including gene loss, gain, function, and the roles Y genes play in stallion fertility. The Cai lab focuses on the interaction between the genotype and phenotype using computational genomics to identify the causal variants underlying genetic disorders and complex traits of different organisms. Projects will focus on applying next-generation sequencing to follow up associations found with more traditional methods. The work is funded by USDA-CREES, USDA-NIFA, American Quarter Horse Foundation, and Morris Animal Foundation. We seek a motivated postdoc that is interested in applying the latest bioinformatics tools to understand the genomic factors that play a role in diseases and phenotypes of horses, and other important domestic, agricultural, and wild animals. The post-doc will be required to write manuscripts and proposals, and will have opportunities to develop additional projects in line with their areas of interest. The successful applicant will work as part of a multidisciplinary team and will develop skills in bioinformatics, genomics, and translational medicine. REQUIREMENTS: Ph.D. in a relevant biological discipline with previous research experience using genomic bioinformatics tools. Knowledge of both genomics and computational analysis of genomic data is required, as is familiarity with Linux, Python, Matlab, and Perl, and the ability to write scripts. Excellent writing, communication skills, and the ability work as part of a team are also required. Previous work with large data sets, SNP analysis, and next-generation sequencing data is preferred. Knowledge and experience with horses, other domestic animals, or wildlife is also preferred. TO APPLY: For inquiries or to apply, email Dr. Jan Janecka (jjanecka@cvm.tamu.edu) a (1) a 1-page cover letter with as summary of your primary research experience and interests, (2) your CV, (3) and contact information for three references. |